Problems got you down? 难题使你沮丧吗?
Problems at work? 工作上出了麻烦吗?
Why so sad? 为何如此悲哀? Why are you so bummed out? 你要死不活地, 是怎么搞的?
Why the long face? 干嘛拉长着脸呢? Why are you pouting? 赌什么气呢?
How do you feel? 好点儿了吗?
I waited on her hand and foot. 我无微不至地照顾她.