Everything in life is relative.There are no absolutes in life. 生命的一切都是相对的没有绝对的事. What difference does it make? 这有什么区别? The difference is so small it's almost imperceptible. 差别很小, 几乎难以看出. I just can't tell them apart. 我简直无法区分他们. The distinguish between these two is blurred. 这两者泾渭难分. It's six of one and half a dozen of the other. 这不是半斤八两吗? These are all one of a kind. 这些都各不相同.
What a big difference it makes! 前后的差异可真大! Time and place can make a difference. 情况常因时、地之不同而异.