The deformed cells block blood vessels and cut off the flow of oxygen to tissue in the body. 变形后的红血球会堵塞血管,切断了向身体内组织的供氧。
People with sickle cell disease can suffer severe pain, bacterial infections and the death of tissue. 患有镰状细胞(贫血)病的人将经受巨痛、细菌感染和组织坏死。
In other studies, bone marrow transplants cure severe sickle cell disease in almost two hundred children. 在其他研究中,骨髓移植治愈了差不多两百名患有严重镰状细胞(贫血)病的孩子。
Doctors first used chemicals to destroy the children's own marrow, then replaced it with health marrow. 医生先用化学药品破坏孩子自有的骨髓,然后用健康的骨髓代替(它)。
However, doctors have considered this treatment too risky for adults with the disease. 然而,医生们认为这种疗法对患有该病的成人太危险。